A stroke is sudden interruption in the blood supply of the brain, which are caused by an abrupt blockage of arteries leading to the brain. According to the American Stroke Association, there are of 3 types of strokes namely ischemic stroke (an obstruction within blood vessel that delivers blood to the brain), hemorrhagic stroke (weakened blood vessel rapture due to high blood pressure), and transient ischemic attack (identified by temporary clot). Stroke can be caused due to medical conditions such as high blood pressure, diabetes, heart disease or life style habits such as smoking, physically inactive lifestyle, alcohol abuse, obesity, and various others. Moreover, uncontrollable factors such as increasing age, male sex, heredity, and ethnicity contribute to stroke. According to the World Health Organization (WHO), in 2015, stroke is the second leading global cause of death after heart disease and it accounted for 11.8% of total deaths worldwide.
Major factors driving growth of the global stroke management market are advancements in technology and therapeutic along with increasing incidence of stroke and stringent approval system.
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Introduction of novel technology and advancement in facilities to diagnose stroke and discovery of novel drugs are expected to drive growth of the global stroke management market during the forecast period. Technologies such as robotic-assisted angiography or exoskeleton soft suit for rehabilitation are driving the market growth. Moreover, in 2003, an idea of Mobile Stroke Treatment Units (MSTU) was introduced in Germany and was used in Berlin for the first time in 2008. The Prehospital Acute Neurological Treatment and Optimization of Medical care in Stroke Study (PHANTOM-S) in Germany reported that their MSTU significantly decreased stroke alert-to-treatment times from 76 minutes to 52 minutes, and significantly increased thrombolysis rates from 21% to 33% with no increase in the risk of intracerebral hemorrhage. Therefore, introduction of novel mobile stroke treatment units is expected to drive growth of the global stroke management market over the forecast period.
Furthermore, conventional stroke treatment aims at minimizing damage caused due to acute stroke by intravenous thrombolytics and endovascular thrombectomy. However, there is no proven cure for reversing the damage. Hence, treatments such robust armamentarium of therapies for stroke treatment such as cell therapy, which has immense potential are expected to propel the market growth in near future. Cell therapy can be used for re-vascularization after stroke and for reduction of cerebral inflammation. Phase II clinical trials of intravenous transplantation of autologous bone-marrow stem cells have reported safety and tolerability in stroke patients. Other pending clinical trials such as PISCES can also be considered as future candidates for clinical practice. Sonothrombolysis is another approach, which uses low-frequency ultrasound waves to cause thrombosis. The prototype for sonothrombolysis device is been tested by North Carolina State University and has filed a patent on the technology.
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Under-equipped or untrained emergency medical service provider and stringent regulatory policies on the approval of new drugs or advanced devices are expected restrain growth of the global stroke management market during the forecast period.
Limited drugs available for the treatment of stroke offers wide opportunities for research organizations and key players to excel in the global stroke management market by discovering novel drugs with less side-effects.
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Key players in the market are focused on various growth strategies such as, partnerships, product development, and merger and acquisition, in order to enhance their presence in the market. For instance, in May 2017, Codman Neuro, a part of Johnson & Johnson acquired Neuravi Ltd., an Irish medical device company that manufactures advance revascularization device and EmboTrap is a device manufactured by this company. The EmboTrap platform was intended to address the critical need for rapid restoration of blood flow in stroke patients and combination of Neuraviโs expertise in clot research with Codman Neuroโs global resources aims to accelerate development in the field of acute ischemic stroke treatment. Furthermore, in 2018, NuvOx Pharmaโs dodecafluoropentane emulsion (DDFPe) IV entered phase II clinical trials and DDFPe aims to deliver oxygen to hypoxic tissue of brain. In 2018, DiaMedica Therapeutics Inc. announced DM199, a recombinant human tissue kallikrein, to enter phase II clinical trial and it is expected to be a breakthrough in stroke treatment.
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On the basis of region, stroke management market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. The significant growth of geriatric population in most of the economies is expected to drive growth of global stroke management market during the forecast period. According to the United Nations Department of Economic and Social Affairs 2015 report, between 2015 and 2030 the number of people in the world at the age of 60 years or above is projected to increase by 56% from 901 million to 1.4 billion. Moreover, over the next 15 years the number of older persons is expected to grow fastest in Latin America and the Caribbean with a projection of around 71%, followed by Asia with 66%, Africa by 64%, and North America by 41%, and Europe by 23% growth in old age population. Furthermore, Asia Pacific is the fastest growing stroke management market region, owing to upsurge in healthcare industry and increasing awareness for healthcare.
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Key companies operating in the global stroke management market are Abbott Laboratories, B. Braun Melsungen AG, Boston Scientific Corporation, GE Healthcare, GlaxoSmithKline Plc, Medtronic Plc, Merck & Co., Inc., and Cardinal Health.
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